C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tryptophan hydroxylase 1b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000036082 tph1b 7955 - 7:34440842-34449394 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000052385 tph1b-001 34440842-34449394 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyMuscleENSDART00000052385
Transcript ID Brain Heart Kidney Muscle
ENSDART00000052385 0.302±0.08 0.345±0.29 1.184±0.41 0.099±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 IEA monooxygenase activity
GO:0004510 IEA tryptophan 5-monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0008152 IEA metabolic process
GO:0009072 IEA aromatic amino acid family metabolic process
GO:0016597 IEA amino acid binding
GO:0016714 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
GO:0042427 IEA serotonin biosynthetic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000129167 TPH1 tryptophan hydroxylase 1 protein_coding Homo_sapiens
ENSMUSG00000040046 Tph1 tryptophan hydroxylase 1 protein_coding Mus_musculus

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