C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aminolevulinate, delta-, synthetase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000038643 alas2 7955 + 8:21891896-21907046 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000056420 alas2-001 21891896-21907046 protein_coding
  ENSDART00000131691 alas2-002 21891945-21894614 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000056420
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000056420 2.660±1.65 98.768±30.46 43.691±15.42 2.440±0.00 4.924±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 ISS response to hypoxia
GO:0003824 IEA catalytic activity
GO:0003870 IEA 5-aminolevulinate synthase activity
GO:0005739 IEA mitochondrion
GO:0005743 ISS mitochondrial inner membrane
GO:0005759 IEA mitochondrial matrix
GO:0006778 IEA porphyrin-containing compound metabolic process
GO:0006782 IEA protoporphyrinogen IX biosynthetic process
GO:0006783 IMP heme biosynthetic process
GO:0008152 IEA metabolic process
GO:0009058 IEA biosynthetic process
GO:0016740 IEA transferase activity
GO:0016746 IEA transferase activity, transferring acyl groups
GO:0020027 IMP hemoglobin metabolic process
GO:0030170 IEA pyridoxal phosphate binding
GO:0030218 ISS erythrocyte differentiation
GO:0033014 IEA tetrapyrrole biosynthetic process
GO:0035162 IMP embryonic hemopoiesis
GO:0042541 ISS hemoglobin biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000158578 ALAS2 aminolevulinate, delta-, synthase 2 protein_coding Homo_sapiens
ENSMUSG00000025270 Alas2 aminolevulinic acid synthase 2, erythroid protein_coding Mus_musculus

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