C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aminolevulinate, delta-, synthase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000158578 ALAS2 9606 - X:55009055-55031064 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330807 ALAS2-006 55009055-55031064 protein_coding
  ENST00000335854 ALAS2-008 55009089-55030977 protein_coding
  ENST00000396198 ALAS2-007 55009055-55030977 protein_coding
  ENST00000455688 ALAS2-004 55020334-55030977 protein_coding
  ENST00000463868 ALAS2-002 55017560-55030977 processed_transcript
  ENST00000477869 ALAS2-005 55017651-55030977 processed_transcript
  ENST00000493869 ALAS2-003 55020425-55030977 processed_transcript
  ENST00000498636 ALAS2-001 55009113-55020433 processed_transcript

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBreastColonHeartLungOvaryPlacentaTestisENST00000330807ENST00000335854ENST00000396198ENST00000455688ENST00000498636
Transcript ID Adipose Bladder Breast Colon Heart Lung Ovary Placenta Testis
ENST00000330807 1.855±0.00 N/A N/A N/A N/A 13.684±0.00 0.882±0.00 9.192±0.87 2.161±0.00
ENST00000335854 2.864±0.00 N/A N/A 7.369±0.00 N/A 23.260±0.00 N/A 7.622±2.00 2.286±0.00
ENST00000396198 N/A 0.306±0.00 N/A N/A N/A N/A N/A 3.972±0.00 N/A
ENST00000455688 N/A N/A 1.129±0.00 N/A 0.150±0.00 N/A N/A N/A N/A
ENST00000498636 N/A N/A N/A N/A N/A 16.434±0.00 N/A 10.940±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YC CIL_0000YC_0001 CGP X:55000357-55031064

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0003870 IDA:IEA 5-aminolevulinate synthase activity
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005759 TAS:IEA mitochondrial matrix
GO:0006778 TAS:IEA porphyrin-containing compound metabolic process
GO:0006782 IEA protoporphyrinogen IX biosynthetic process
GO:0006783 ISS heme biosynthetic process
GO:0006879 ISS cellular iron ion homeostasis
GO:0008152 IEA metabolic process
GO:0009058 IEA biosynthetic process
GO:0016594 ISS glycine binding
GO:0030170 IEA pyridoxal phosphate binding
GO:0030218 ISS erythrocyte differentiation
GO:0032364 NAS oxygen homeostasis
GO:0033014 IEA tetrapyrrole biosynthetic process
GO:0042541 ISS hemoglobin biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0050662 ISS coenzyme binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038643 alas2 aminolevulinate, delta-, synthetase 2 protein_coding Danio_rerio
ENSMUSG00000025270 Alas2 aminolevulinic acid synthase 2, erythroid protein_coding Mus_musculus

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