C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000039684 sirt5 7955 - 20:7225779-7244340 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000040793 sirt5-001 7227598-7244340 protein_coding
  ENSDART00000121704 sirt5-201 7225779-7241802 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000040793ENSDART00000121704
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000040793 3.995±3.13 6.329±4.55 2.404±1.45 0.277±0.00 4.221±0.00
ENSDART00000121704 2.362±1.07 1.810±0.61 0.711±0.00 0.136±0.00 1.848±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005739 IEA mitochondrion
GO:0008270 ISS zinc ion binding
GO:0016787 IEA hydrolase activity
GO:0036047 ISS peptidyl-lysine demalonylation
GO:0036049 ISS peptidyl-lysine desuccinylation
GO:0036054 IEA protein-malonyllysine demalonylase activity
GO:0036055 IEA protein-succinyllysine desuccinylase activity
GO:0046872 IEA metal ion binding
GO:0070403 IEA NAD+ binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000124523 SIRT5 sirtuin 5 protein_coding Homo_sapiens
ENSMUSG00000054021 Sirt5 sirtuin 5 protein_coding Mus_musculus

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