C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sirtuin 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000054021 Sirt5 10090 + 13:43370710-43395202 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000066804 Sirt5-201 43370710-43395202 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066804
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066804 3.845±1.97 3.387±0.11 7.626±7.40 1.600±0.68 3.793±1.30 3.473±1.25 2.753±1.20 2.408±1.71 1.995±1.59 2.830±1.35 4.453±1.94 1.811±0.31 1.132±0.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008MO CIL_0008MO_0002 VISTA 13:42895920-43497079
CIL_0003IA CIL_0003IA_0002 CGP 13:43195519-43395202
CIL_0003I9 CIL_0003I9_0002 CGP 13:43370710-43402858

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005739 ISS mitochondrion
GO:0005758 ISS mitochondrial intermembrane space
GO:0005759 ISS mitochondrial matrix
GO:0005829 IDA cytosol
GO:0006476 ISS protein deacetylation
GO:0008270 IEA zinc ion binding
GO:0036047 IMP peptidyl-lysine demalonylation
GO:0036048 IMP protein desuccinylation
GO:0036049 IMP peptidyl-lysine desuccinylation
GO:0036054 IMP protein-malonyllysine demalonylase activity
GO:0036055 IMP protein-succinyllysine desuccinylase activity
GO:0070403 IEA NAD+ binding
GO:2000378 IEA negative regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039684 sirt5 sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae) protein_coding Danio_rerio
ENSG00000124523 SIRT5 sirtuin 5 protein_coding Homo_sapiens

Loading