C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000039934 hlcs 7955 + 10:224964-230364 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000058411 hlcs-201 224994-230364 protein_coding
  ENSDART00000128556 hlcs-202 224964-230364 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000058411ENSDART00000128556
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000058411 N/A 0.994±0.00 N/A N/A 2.789±0.00
ENSDART00000128556 6.345±4.96 6.492±0.00 0.512±0.00 3.969±0.00 9.652±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004077 IEA biotin-[acetyl-CoA-carboxylase] ligase activity
GO:0006464 IEA cellular protein modification process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000159267 HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) protein_coding Homo_sapiens
ENSMUSG00000040820 Hlcs holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase) protein_coding Mus_musculus

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