C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040820 Hlcs 10090 - 16:94129195-94313563 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000099512 Hlcs-201 94129306-94287856 protein_coding
  ENSMUST00000163193 Hlcs-202 94129195-94313563 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000099512ENSMUST00000163193
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000099512 2.286±0.13 N/A 1.158±0.85 1.570±0.00 2.653±0.00 0.477±0.00 0.966±0.01 0.569±0.28 1.129±0.00 0.861±0.32 2.371±0.25 1.152±0.19 0.546±0.37
ENSMUST00000163193 1.949±1.76 1.414±0.07 0.432±0.30 1.424±0.82 N/A 0.780±0.31 0.583±0.17 0.511±0.26 0.959±0.35 0.851±0.35 1.812±1.19 1.229±0.62 0.480±0.26

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006Z8 CIL_0006Z8_0002 CGP 16:94085260-94313563
CIL_0006ZF CIL_0006ZF_0002 CGP 16:94129195-94336935

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000785 ISS chromatin
GO:0004077 IEA biotin-[acetyl-CoA-carboxylase] ligase activity
GO:0004078 IEA biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity
GO:0004079 IEA biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity
GO:0004080 ISS biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005652 ISS nuclear lamina
GO:0005737 ISS cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 ISS cytosol
GO:0008283 ISS cell proliferation
GO:0009305 ISS protein biotinylation
GO:0009374 ISS biotin binding
GO:0016363 ISS nuclear matrix
GO:0016570 ISS histone modification
GO:0018271 ISS biotin-protein ligase activity
GO:0019899 ISS enzyme binding
GO:0042803 ISS protein homodimerization activity
GO:0070781 ISS response to biotin
GO:0071110 ISS histone biotinylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039934 hlcs holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase) protein_coding Danio_rerio
ENSG00000159267 HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) protein_coding Homo_sapiens

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