C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: platelet-derived growth factor beta polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000040839 PDGFB (2 of 3) 7955 - 22:32004092-32027550 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000059856 PDGFB (2 of 3)-202 32004092-32027166 protein_coding
  ENSDART00000125660 PDGFB (2 of 3)-001 32008376-32027550 protein_coding
  ENSDART00000129144 PDGFB (2 of 3)-201 32007276-32027165 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000059856ENSDART00000125660ENSDART00000129144
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000059856 0.729±0.43 0.851±0.54 0.767±0.00 0.047±0.00 0.976±0.00
ENSDART00000125660 0.379±0.14 N/A N/A 0.052±0.00 N/A
ENSDART00000129144 N/A N/A N/A 0.027±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005161 IBA platelet-derived growth factor receptor binding
GO:0005615 IBA extracellular space
GO:0007596 IBA blood coagulation
GO:0008083 IEA growth factor activity
GO:0008284 IBA positive regulation of cell proliferation
GO:0014068 IBA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IEA membrane
GO:0030335 IBA positive regulation of cell migration
GO:0031954 IBA positive regulation of protein autophosphorylation
GO:0043406 IBA positive regulation of MAP kinase activity
GO:0048008 IBA platelet-derived growth factor receptor signaling pathway
GO:0070374 IBA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000100311 PDGFB platelet-derived growth factor beta polypeptide protein_coding Homo_sapiens
ENSMUSG00000000489 Pdgfb platelet derived growth factor, B polypeptide protein_coding Mus_musculus

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