C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: rho/rac guanine nucleotide exchange factor (GEF) 18b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000042308 arhgef18b 7955 - 22:10920811-11008467 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000010991 arhgef18b-201 10920811-11008467 protein_coding
  ENSDART00000145229 arhgef18b-001 10924354-11001363 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000010991ENSDART00000145229
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000010991 2.331±0.51 2.477±1.23 3.611±0.27 N/A 0.347±0.00
ENSDART00000145229 N/A N/A N/A 0.135±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000104880 ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 protein_coding Homo_sapiens
ENSG00000268861 CTD-2207O23.3 Rho guanine nucleotide exchange factor 18 {ECO:0000313|Ensembl:ENSP00000471597} protein_coding Homo_sapiens
ENSMUSG00000004568 Arhgef18 rho/rac guanine nucleotide exchange factor (GEF) 18 protein_coding Mus_musculus

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