C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: rho/rac guanine nucleotide exchange factor (GEF) 18
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000004568 Arhgef18 10090 + 8:3393006-3456601 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000004684 Arhgef18-001 3393038-3456601 protein_coding
  ENSMUST00000130587 Arhgef18-005 3393073-3429271 processed_transcript
  ENSMUST00000131773 Arhgef18-002 3393006-3450640 retained_intron
  ENSMUST00000145360 Arhgef18-006 3450758-3454268 retained_intron
  ENSMUST00000145394 Arhgef18-004 3393073-3429639 protein_coding
  ENSMUST00000156085 Arhgef18-003 3437011-3456600 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000004684ENSMUST00000131773ENSMUST00000145360
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000004684 12.570±1.07 15.481±2.06 15.082±0.73 8.516±0.52 20.661±8.58 13.580±1.58 4.632±0.69 15.490±3.26 5.328±1.85 24.770±2.08 1.834±0.39 13.840±1.81 22.393±17.93 2.867±0.94
ENSMUST00000131773 N/A N/A N/A N/A 4.430±0.00 N/A 1.098±0.07 N/A N/A N/A N/A N/A N/A 1.012±0.00
ENSMUST00000145360 N/A 8.672±1.23 N/A N/A 19.390±0.00 14.760±3.43 N/A N/A N/A N/A N/A 18.915±2.83 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004YI CIL_0004YI_0002 CGP 8:3353415-3456601
CIL_0002U4 CIL_0002U4_0002 CGP 8:3393006-3467680

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005737 IEA cytoplasm
GO:0032321 IEA positive regulation of Rho GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011157 arhgef18a rho/rac guanine nucleotide exchange factor (GEF) 18a protein_coding Danio_rerio
ENSDARG00000042308 arhgef18b rho/rac guanine nucleotide exchange factor (GEF) 18b protein_coding Danio_rerio
ENSG00000104880 ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 protein_coding Homo_sapiens
ENSG00000268861 CTD-2207O23.3 Rho guanine nucleotide exchange factor 18 {ECO:0000313|Ensembl:ENSP00000471597} protein_coding Homo_sapiens

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