C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000042684 serpinc1 7955 + 22:16168371-16174351 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000062618 serpinc1-001 16168371-16174351 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000062618
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000062618 2.248±0.56 6.161±2.93 74.241±23.16 85.386±0.00 5.207±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005CR CIL_0005CR_0001 CGP 22:16119282-16174351
CIL_0005CS CIL_0005CS_0001 CGP 22:16168371-16180297

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IEA serine-type endopeptidase inhibitor activity
GO:0005576 IBA extracellular region
GO:0005615 IEA extracellular space
GO:0008201 IEA heparin binding
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0071391 IDA cellular response to estrogen stimulus
GO:2000266 IEA regulation of blood coagulation, intrinsic pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000117601 SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 protein_coding Homo_sapiens
ENSMUSG00000026715 Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 protein_coding Mus_musculus

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