C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serpin peptidase inhibitor, clade C (antithrombin), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117601 SERPINC1 9606 - 1:173903804-173917378 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000367698 SERPINC1-001 173903809-173917378 protein_coding
  ENST00000487183 SERPINC1-003 173909730-173914665 processed_transcript
  ENST00000494024 SERPINC1-002 173911980-173917316 processed_transcript
  ENST00000617423 SERPINC1-201 173903804-173917378 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367698ENST00000487183ENST00000494024ENST00000617423
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367698 N/A 0.029±0.00 0.251±0.00 N/A 0.526±0.51 N/A 0.026±0.00 930.775±0.00 358.349±358.31 N/A 0.242±0.00 N/A 0.134±0.03 0.213±0.00
ENST00000487183 0.048±0.00 N/A N/A 0.082±0.00 N/A N/A N/A 0.202±0.00 N/A 0.435±0.00 0.409±0.00 0.064±0.01 N/A N/A
ENST00000494024 N/A N/A N/A N/A 0.039±0.00 0.051±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000617423 N/A 0.080±0.00 N/A 0.017±0.00 1.010±0.00 N/A 0.358±0.29 N/A N/A N/A 0.312±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IPI protease binding
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0005615 IDA extracellular space
GO:0005886 TAS plasma membrane
GO:0007584 IEA response to nutrient
GO:0007596 TAS blood coagulation
GO:0008201 IEA heparin binding
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0050728 IEA negative regulation of inflammatory response
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle
GO:2000266 IEA regulation of blood coagulation, intrinsic pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042684 serpinc1 serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1 protein_coding Danio_rerio
ENSMUSG00000026715 Serpinc1 serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 protein_coding Mus_musculus

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