C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026715 Serpinc1 10090 + 1:160978606-161003010 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000064725 Serpinc1-201 160978606-161003010 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000064725
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000064725 0.224±0.10 0.539±0.47 0.073±0.02 0.232±0.00 1.682±1.49 0.228±0.11 0.174±0.15 0.342±0.11 528.136±408.03 0.280±0.08 0.032±0.02 1.113±0.32 6.900±8.96 0.198±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005CR CIL_0005CR_0002 CGP 1:160906418-161003010
CIL_0005CS CIL_0005CS_0002 CGP 1:160978606-161034849

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002020 IEA protease binding
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005576 IBA extracellular region
GO:0005615 IEA extracellular space
GO:0007584 IEA response to nutrient
GO:0007596 IEA blood coagulation
GO:0008201 IEA heparin binding
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0050728 IEA negative regulation of inflammatory response
GO:0070062 IEA extracellular vesicular exosome
GO:0072562 IEA blood microparticle
GO:2000266 IEA regulation of blood coagulation, intrinsic pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042684 serpinc1 serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1 protein_coding Danio_rerio
ENSG00000117601 SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 protein_coding Homo_sapiens

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