Institute of Cardiovascular Regeneration Webtool Repository

Warning (512): _cake_core_ cache was unable to write 'cake_dev_eng' to File cache [CORE/Cake/Cache/Cache.php, line 323]

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                ),
                E_USER_WARNING
            );

$key = 'cake_dev_eng'
$value = array(
	'LC_MESSAGES' => array()
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false

Cache::write() - CORE/Cake/Cache/Cache.php, line 323
I18n::translate() - CORE/Cake/I18n/I18n.php, line 237
__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_citloci_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]

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                ),
                E_USER_WARNING
            );

$key = 'default_citloci_list'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false

Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_citloci_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]

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                ),
                E_USER_WARNING
            );

$key = 'default_citloci_list'
$value = array(
	(int) 0 => 'conserved_region_elements',
	(int) 1 => 'conserved_regions',
	(int) 2 => 'diffexp',
	(int) 3 => 'experiment',
	(int) 4 => 'expressed_transcripts',
	(int) 5 => 'external_accessions',
	(int) 6 => 'genes',
	(int) 7 => 'go_annotations',
	(int) 8 => 'homologues',
	(int) 9 => 'maptranscripttoregion',
	(int) 10 => 'organism',
	(int) 11 => 'sample',
	(int) 12 => 'study',
	(int) 13 => 'synonyms',
	(int) 14 => 'transcripts'
)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false

Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_citloci_genes' to File cache [CORE/Cake/Cache/Cache.php, line 323]

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                ),
                E_USER_WARNING
            );

$key = 'default_citloci_genes'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false

Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
DataSource::describe() - CORE/Cake/Model/Datasource/DataSource.php, line 135
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 332
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165

Warning (512): _cake_model_ cache was unable to write 'default_citloci_genes' to File cache [CORE/Cake/Cache/Cache.php, line 323]

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                ),
                E_USER_WARNING
            );

$key = 'default_citloci_genes'
$value = array(
	'id' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 32,
		'key' => 'primary',
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'gene_version' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'tax_id' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'assembly' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'chromosome' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'strand' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'start' => array(
		'type' => 'integer',
		'null' => false,
		'default' => null,
		'length' => (int) 11,
		'unsigned' => false
	),
	'end' => array(
		'type' => 'integer',
		'null' => false,
		'default' => null,
		'length' => (int) 11,
		'unsigned' => false
	),
	'gene_name' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'gene_source' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'gene_biotype' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 128,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'annotation_version' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'gene_description' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 128,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	)
)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false

Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 372
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Gene Info
Description:	tau tubulin kinase 2
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSDARG00000043026	TTBK2 (2 of 2)	7955	+	20:25940949-25957962	protein_coding
	Transcript Accession	Transcript Name	Position	Transcript Biotype
	ENSDART00000063168	TTBK2 (2 of 2)-201	25945410-25957890	protein_coding
	ENSDART00000146004	TTBK2 (2 of 2)-001	25940949-25957962	protein_coding

Gene Info

Description:

tau tubulin kinase 2

Gene Accession

Gene Name

Tax ID

Strand

Position

Gene Biotype

ENSDARG00000043026

TTBK2 (2 of 2)

7955

20:25940949-25957962

protein_coding

Transcript Accession

Transcript Name

Position

Transcript Biotype

ENSDART00000063168

TTBK2 (2 of 2)-201

25945410-25957890

protein_coding

ENSDART00000146004

TTBK2 (2 of 2)-001

25940949-25957962

protein_coding

Transcript ID	Brain	Heart	Kidney	Liver	Muscle
ENSDART00000063168	3.176±1.52	1.284±0.43	1.660±0.24	0.256±0.00	0.752±0.00
ENSDART00000146004	9.689±2.87	0.606±0.19	0.880±0.00	0.411±0.00	0.157±0.00

Conserved Regions
Gene is not located within a conserved region.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0000166	IEA	nucleotide binding
GO:0004672	IEA	protein kinase activity
GO:0004713	IEA	protein tyrosine kinase activity
GO:0005524	IEA	ATP binding
GO:0006468	IEA	protein phosphorylation
GO:0016772	IEA	transferase activity, transferring phosphorus-containing groups

Gene Ontology

GO ID

Evidence Type

GO Description

GO:0000166

IEA

nucleotide binding

GO:0004672

IEA

protein kinase activity

GO:0004713

IEA

protein tyrosine kinase activity

GO:0005524

IEA

ATP binding

GO:0006468

IEA

protein phosphorylation

GO:0016772

IEA

transferase activity, transferring phosphorus-containing groups

Warning (512): _cake_core_ cache was unable to write 'file_map' to File cache [CORE/Cake/Cache/Cache.php, line 323]

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                ),
                E_USER_WARNING
            );

$key = 'file_map'
$value = array(
	'Configure' => '/var/www/c-it-loci/lib/Cake/Core/Configure.php',
	'Hash' => '/var/www/c-it-loci/lib/Cake/Utility/Hash.php',
	'Cache' => '/var/www/c-it-loci/lib/Cake/Cache/Cache.php',
	'FileEngine' => '/var/www/c-it-loci/lib/Cake/Cache/Engine/FileEngine.php',
	'CacheEngine' => '/var/www/c-it-loci/lib/Cake/Cache/CacheEngine.php',
	'Inflector' => '/var/www/c-it-loci/lib/Cake/Utility/Inflector.php',
	'ErrorHandler' => '/var/www/c-it-loci/lib/Cake/Error/ErrorHandler.php',
	'CakePlugin' => '/var/www/c-it-loci/lib/Cake/Core/CakePlugin.php',
	'CakeLog' => '/var/www/c-it-loci/lib/Cake/Log/CakeLog.php',
	'LogEngineCollection' => '/var/www/c-it-loci/lib/Cake/Log/LogEngineCollection.php',
	'ObjectCollection' => '/var/www/c-it-loci/lib/Cake/Utility/ObjectCollection.php',
	'FileLog' => '/var/www/c-it-loci/lib/Cake/Log/Engine/FileLog.php',
	'BaseLog' => '/var/www/c-it-loci/lib/Cake/Log/Engine/BaseLog.php',
	'CakeLogInterface' => '/var/www/c-it-loci/lib/Cake/Log/CakeLogInterface.php',
	'Debugger' => '/var/www/c-it-loci/lib/Cake/Utility/Debugger.php',
	'String' => '/var/www/c-it-loci/lib/Cake/Utility/String.php',
	'Dispatcher' => '/var/www/c-it-loci/lib/Cake/Routing/Dispatcher.php',
	'CakeEventListener' => '/var/www/c-it-loci/lib/Cake/Event/CakeEventListener.php',
	'CakeRequest' => '/var/www/c-it-loci/lib/Cake/Network/CakeRequest.php',
	'CakeResponse' => '/var/www/c-it-loci/lib/Cake/Network/CakeResponse.php',
	'CakeEvent' => '/var/www/c-it-loci/lib/Cake/Event/CakeEvent.php',
	'CakeEventManager' => '/var/www/c-it-loci/lib/Cake/Event/CakeEventManager.php',
	'AssetDispatcher' => '/var/www/c-it-loci/lib/Cake/Routing/Filter/AssetDispatcher.php',
	'DispatcherFilter' => '/var/www/c-it-loci/lib/Cake/Routing/DispatcherFilter.php',
	'CacheDispatcher' => '/var/www/c-it-loci/lib/Cake/Routing/Filter/CacheDispatcher.php',
	'Router' => '/var/www/c-it-loci/lib/Cake/Routing/Router.php',
	'CakeRoute' => '/var/www/c-it-loci/lib/Cake/Routing/Route/CakeRoute.php',
	'PluginShortRoute' => '/var/www/c-it-loci/lib/Cake/Routing/Route/PluginShortRoute.php',
	'GeneController' => '/var/www/c-it-loci/app/Controller/GeneController.php',
	'AppController' => '/var/www/c-it-loci/app/Controller/AppController.php',
	'Controller' => '/var/www/c-it-loci/lib/Cake/Controller/Controller.php',
	'Object' => '/var/www/c-it-loci/lib/Cake/Core/Object.php',
	'ComponentCollection' => '/var/www/c-it-loci/lib/Cake/Controller/ComponentCollection.php',
	'SessionComponent' => '/var/www/c-it-loci/lib/Cake/Controller/Component/SessionComponent.php',
	'Component' => '/var/www/c-it-loci/lib/Cake/Controller/Component.php',
	'RequestHandlerComponent' => '/var/www/c-it-loci/lib/Cake/Controller/Component/RequestHandlerComponent.php',
	'ClassRegistry' => '/var/www/c-it-loci/lib/Cake/Utility/ClassRegistry.php',
	'Gene' => '/var/www/c-it-loci/app/Model/Gene.php',
	'AppModel' => '/var/www/c-it-loci/app/Model/AppModel.php',
	'Model' => '/var/www/c-it-loci/lib/Cake/Model/Model.php',
	'BehaviorCollection' => '/var/www/c-it-loci/lib/Cake/Model/BehaviorCollection.php',
	'ConnectionManager' => '/var/www/c-it-loci/lib/Cake/Model/ConnectionManager.php',
	'Mysql' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/Database/Mysql.php',
	'DboSource' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/DboSource.php',
	'DataSource' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/DataSource.php',
	'I18n' => '/var/www/c-it-loci/lib/Cake/I18n/I18n.php',
	'L10n' => '/var/www/c-it-loci/lib/Cake/I18n/L10n.php',
	'CakeSession' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/CakeSession.php',
	'View' => '/var/www/c-it-loci/lib/Cake/View/View.php',
	'HelperCollection' => '/var/www/c-it-loci/lib/Cake/View/HelperCollection.php',
	'ViewBlock' => '/var/www/c-it-loci/lib/Cake/View/ViewBlock.php',
	'HtmlHelper' => '/var/www/c-it-loci/lib/Cake/View/Helper/HtmlHelper.php',
	'AppHelper' => '/var/www/c-it-loci/app/View/Helper/AppHelper.php',
	'Helper' => '/var/www/c-it-loci/lib/Cake/View/Helper.php',
	'FormHelper' => '/var/www/c-it-loci/lib/Cake/View/Helper/FormHelper.php',
	'SessionHelper' => '/var/www/c-it-loci/lib/Cake/View/Helper/SessionHelper.php'
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false

Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ??

Warning (512): _cake_core_ cache was unable to write 'method_cache' to File cache [CORE/Cake/Cache/Cache.php, line 323]

Code Context

                ),
                E_USER_WARNING
            );

$key = 'method_cache'
$value = array(
	(int) 0 => false,
	'name' => array(
		'45b989c52610ac6d773f6b83d6108190' => '`citloci`',
		'4d0d73f550e4b0573d9cf666d63a0244' => '`genes`',
		'003d5968b53baeeb0cb27d56c4d447af' => '`Gene`.`id`',
		'f32f1dc049466870a2299961f0604112' => '`Gene`.`gene_version`',
		'433a39b330b04a021541e6fa89d80ffd' => '`Gene`.`tax_id`',
		'56705ff3488da428f13156180dbc9fbc' => '`Gene`.`assembly`',
		'b7d572bb36c8f0f2ecfe36921c14fbf3' => '`Gene`.`chromosome`',
		'edf6b12f8a40424f91fa0a40f0eab275' => '`Gene`.`strand`',
		'71d92ec0ad29837870abd0de3ae8addc' => '`Gene`.`start`',
		'62e43d606bf4cdae2d6694c62e19e7fa' => '`Gene`.`end`',
		'7043386674301bd31c5e629dfdadabd4' => '`Gene`.`gene_name`',
		'f1454297621ddcf07c418e47f67d3857' => '`Gene`.`gene_source`',
		'27d53785bfcd771f1901030b4bb87d02' => '`Gene`.`gene_biotype`',
		'b93574bf8a03f2d6f6486e920115e0d1' => '`Gene`.`annotation_version`',
		'1c4a3f5d90070e8ea1c62ca077df603e' => '`Gene`.`gene_description`',
		'8ca7a0c53312b8ae3cfa40a9d814adac' => '`Gene`'
	),
	'fields' => array(
		'0ea8c82680a14e2566476c4ab527af47' => array(
			(int) 0 => '`Gene`.`id`',
			(int) 1 => '`Gene`.`gene_version`',
			(int) 2 => '`Gene`.`tax_id`',
			(int) 3 => '`Gene`.`assembly`',
			(int) 4 => '`Gene`.`chromosome`',
			(int) 5 => '`Gene`.`strand`',
			(int) 6 => '`Gene`.`start`',
			(int) 7 => '`Gene`.`end`',
			(int) 8 => '`Gene`.`gene_name`',
			(int) 9 => '`Gene`.`gene_source`',
			(int) 10 => '`Gene`.`gene_biotype`',
			(int) 11 => '`Gene`.`annotation_version`',
			(int) 12 => '`Gene`.`gene_description`'
		)
	)
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
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DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
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C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Expression Patterns

Conserved Regions

Gene Ontology

Homologs

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Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSG00000128881	TTBK2	tau tubulin kinase 2	protein_coding	Homo_sapiens
ENSMUSG00000090100	Ttbk2	tau tubulin kinase 2	protein_coding	Mus_musculus