C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tau tubulin kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000090100 Ttbk2 10090 - 2:120732816-120850604 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028740 Ttbk2-002 120732816-120850604 protein_coding
  ENSMUST00000057135 Ttbk2-001 120732816-120850406 protein_coding
  ENSMUST00000085840 Ttbk2-201 120732816-120850418 protein_coding
  ENSMUST00000131389 Ttbk2-004 120750234-120850364 protein_coding
  ENSMUST00000141921 Ttbk2-005 120790340-120850435 processed_transcript
  ENSMUST00000143051 Ttbk2-003 120745671-120850390 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000028740ENSMUST00000057135ENSMUST00000085840ENSMUST00000141921ENSMUST00000143051
Transcript ID Bladder Brain Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000028740 N/A 4.346±0.00 N/A N/A N/A N/A 0.728±0.16 4.020±1.43 1.106±0.15 12.042±1.12
ENSMUST00000057135 2.179±0.34 6.043±2.09 N/A 1.319±0.08 1.406±0.51 N/A 0.832±0.20 1.847±0.00 0.647±0.00 N/A
ENSMUST00000085840 N/A 4.897±1.23 1.640±0.19 N/A 0.789±0.00 0.545±0.04 0.952±0.21 N/A 1.220±0.24 N/A
ENSMUST00000141921 N/A N/A N/A N/A N/A N/A N/A N/A N/A 306.108±0.00
ENSMUST00000143051 N/A N/A N/A N/A N/A N/A N/A N/A N/A 55.568±27.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005PG CIL_0005PG_0002 CGP 2:120629126-120850128
CIL_0005YE CIL_0005YE_0002 CGP 2:120716154-120850604
CIL_0005YF CIL_0005YF_0002 CGP 2:120732816-120970715

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IMP protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0005634 ISS nucleus
GO:0005814 IDA centriole
GO:0005829 IEA cytosol
GO:0006468 IEA protein phosphorylation
GO:0007224 IMP smoothened signaling pathway
GO:0018105 ISS peptidyl-serine phosphorylation
GO:0035869 IDA ciliary transition zone
GO:0036064 IDA ciliary basal body
GO:0042384 IMP cilium assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005670 ttbk2 tau tubulin kinase 2 protein_coding Danio_rerio
ENSDARG00000043026 TTBK2 (2 of 2) tau tubulin kinase 2 protein_coding Danio_rerio
ENSG00000128881 TTBK2 tau tubulin kinase 2 protein_coding Homo_sapiens

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