C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tau tubulin kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128881 TTBK2 9606 - 15:42738734-42920809 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000267890 TTBK2-001 42738734-42920479 protein_coding
  ENST00000562880 TTBK2-006 42829941-42908275 protein_coding
  ENST00000564431 TTBK2-007 42827977-42920761 protein_coding
  ENST00000566931 TTBK2-008 42829970-42920638 protein_coding
  ENST00000567274 TTBK2-003 42776950-42920762 protein_coding
  ENST00000567485 TTBK2-005 42855119-42919788 processed_transcript
  ENST00000567840 TTBK2-002 42776918-42920809 protein_coding
  ENST00000622375 TTBK2-201 42744352-42920809 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000267890ENST00000567840ENST00000622375
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000267890 1.915±0.00 1.107±0.00 4.310±1.28 0.188±0.00 1.271±0.04 1.570±0.47 1.032±0.00 1.371±1.18 1.164±0.78 0.255±0.00 0.737±0.39 0.486±0.22 2.158±0.62
ENST00000567840 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.162±0.00
ENST00000622375 N/A 0.600±0.00 N/A 0.979±0.00 0.630±0.00 0.419±0.00 N/A 0.621±0.00 N/A 0.459±0.00 N/A N/A 6.099±2.34

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005YE CIL_0005YE_0001 CGP 15:42723559-42920809
CIL_0005YF CIL_0005YF_0001 CGP 15:42738734-43106113

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005814 IEA centriole
GO:0005829 IDA cytosol
GO:0005882 IEA intermediate filament
GO:0006468 IEA protein phosphorylation
GO:0007224 ISS smoothened signaling pathway
GO:0008219 IEA cell death
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0035869 ISS ciliary transition zone
GO:0036064 ISS ciliary basal body
GO:0042384 ISS cilium assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005670 ttbk2 tau tubulin kinase 2 protein_coding Danio_rerio
ENSDARG00000043026 TTBK2 (2 of 2) tau tubulin kinase 2 protein_coding Danio_rerio
ENSMUSG00000090100 Ttbk2 tau tubulin kinase 2 protein_coding Mus_musculus

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