C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: steroid 5 alpha-reductase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000043307 srd5a3 7955 - 20:22266478-22271142 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000063578 srd5a3-001 22266478-22271142 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000063578
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000063578 7.584±2.44 6.656±4.43 9.886±0.00 0.317±0.00 2.244±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003865 ISS 3-oxo-5-alpha-steroid 4-dehydrogenase activity
GO:0005737 IEA cytoplasm
GO:0005783 ISS endoplasmic reticulum
GO:0005789 IEA endoplasmic reticulum membrane
GO:0006486 IEA protein glycosylation
GO:0006488 ISS dolichol-linked oligosaccharide biosynthetic process
GO:0006629 IEA lipid metabolic process
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016095 ISS polyprenol catabolic process
GO:0016491 IEA oxidoreductase activity
GO:0016627 IEA oxidoreductase activity, acting on the CH-CH group of donors
GO:0016628 ISS oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0019348 ISS dolichol metabolic process
GO:0047751 IEA cholestenone 5-alpha-reductase activity
GO:0055114 ISS oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000128039 SRD5A3 steroid 5 alpha-reductase 3 protein_coding Homo_sapiens
ENSMUSG00000029233 Srd5a3 steroid 5 alpha-reductase 3 protein_coding Mus_musculus

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