C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: steroid-5-alpha-reductase, alpha polypeptide 2a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000043587 srd5a2a 7955 + 1:51575993-51582450 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000064007 srd5a2a-001 51575993-51582450 protein_coding
  ENSDART00000123527 srd5a2a-003 51576104-51582429 nonsense_mediated_decay
  ENSDART00000140655 srd5a2a-002 51576138-51582450 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000064007ENSDART00000123527ENSDART00000140655
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000064007 N/A 4.061±1.83 21.054±4.66 6.246±0.00 2.082±0.00
ENSDART00000123527 N/A N/A 88.844±41.63 N/A N/A
ENSDART00000140655 0.447±0.00 1.457±0.00 2.382±0.00 N/A 0.735±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003865 IEA 3-oxo-5-alpha-steroid 4-dehydrogenase activity
GO:0005737 IEA cytoplasm
GO:0006629 IEA lipid metabolic process
GO:0008202 IEA steroid metabolic process
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016627 IEA oxidoreductase activity, acting on the CH-CH group of donors
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000277893 SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) protein_coding Homo_sapiens
ENSMUSG00000038541 Srd5a2 steroid 5 alpha-reductase 2 protein_coding Mus_musculus

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