C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: steroid 5 alpha-reductase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038541 Srd5a2 10090 - 17:74017706-74047916 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000043458 Srd5a2-201 74017706-74047916 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000043458
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000043458 0.149±0.06 431.534±399.86 0.023±0.00 0.070±0.01 0.785±0.36 0.036±0.00 1.853±0.68 0.556±0.53 0.082±0.03 0.981±0.44 0.016±0.01 0.394±0.30

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000VC CIL_0000VC_0002 CGP 17:73883908-74047916
CIL_0003JI CIL_0003JI_0003 CGP 17:74017706-74294883

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003865 IMP 3-oxo-5-alpha-steroid 4-dehydrogenase activity
GO:0005783 IEA endoplasmic reticulum
GO:0006694 IMP steroid biosynthetic process
GO:0006702 IMP androgen biosynthetic process
GO:0006706 IEA steroid catabolic process
GO:0008209 IEA androgen metabolic process
GO:0008584 IEA male gonad development
GO:0009917 IEA sterol 5-alpha reductase activity
GO:0010033 IEA response to organic substance
GO:0014070 IEA response to organic cyclic compound
GO:0016021 IEA integral component of membrane
GO:0018879 IEA biphenyl metabolic process
GO:0018894 IEA dibenzo-p-dioxin metabolic process
GO:0018963 IEA phthalate metabolic process
GO:0021766 IEA hippocampus development
GO:0021854 IEA hypothalamus development
GO:0030154 IEA cell differentiation
GO:0030539 IMP male genitalia development
GO:0030540 IEA female genitalia development
GO:0031667 IEA response to nutrient levels
GO:0032354 IEA response to follicle-stimulating hormone
GO:0033218 IEA amide binding
GO:0033574 IEA response to testosterone
GO:0042493 IEA response to drug
GO:0043025 IEA neuronal cell body
GO:0043434 IEA response to peptide hormone
GO:0047751 IEA cholestenone 5-alpha-reductase activity
GO:0048545 IEA response to steroid hormone
GO:0055114 IEA oxidation-reduction process
GO:0060348 IEA bone development
GO:0070852 IEA cell body fiber

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000039067 srd5a2b steroid-5-alpha-reductase, alpha polypeptide 2b protein_coding Danio_rerio
ENSDARG00000043587 srd5a2a steroid-5-alpha-reductase, alpha polypeptide 2a protein_coding Danio_rerio
ENSG00000277893 SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) protein_coding Homo_sapiens

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