C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tumor protein p63
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000044356 tp63 7955 + 6:28509576-28628021 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000065135 tp63-002 28591127-28628013 protein_coding
  ENSDART00000065137 tp63-001 28591102-28628021 protein_coding
  ENSDART00000123189 tp63-005 28591112-28624640 protein_coding
  ENSDART00000127965 tp63-003 28509576-28627336 protein_coding
  ENSDART00000130799 tp63-004 28591237-28626964 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000065135ENSDART00000065137ENSDART00000123189ENSDART00000127965ENSDART00000130799
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000065135 1.805±0.00 1.393±0.42 6.394±0.54 0.052±0.00 N/A
ENSDART00000065137 N/A N/A 0.248±0.00 N/A N/A
ENSDART00000123189 N/A 1.984±0.00 N/A N/A 0.926±0.00
ENSDART00000127965 N/A N/A N/A N/A 0.560±0.00
ENSDART00000130799 N/A N/A N/A 0.031±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003Y5 CIL_0003Y5_0001 CGP 6:28466739-28628021

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IBA negative regulation of transcription from RNA polymerase II promoter
GO:0000785 IBA chromatin
GO:0002039 IBA p53 binding
GO:0003677 IEA DNA binding
GO:0003682 IBA chromatin binding
GO:0003684 IBA damaged DNA binding
GO:0003690 IBA double-stranded DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005667 IBA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0005829 IBA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0006915 IEA apoptotic process
GO:0006978 IBA DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0007049 IEA cell cycle
GO:0007417 IGI central nervous system development
GO:0010165 IBA response to X-ray
GO:0010332 IBA response to gamma radiation
GO:0030425 IBA dendrite
GO:0031571 IBA mitotic G1 DNA damage checkpoint
GO:0034644 IBA cellular response to UV
GO:0042771 IBA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0043523 IBA regulation of neuron apoptotic process
GO:0043565 IBA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-dependent
GO:0046872 IEA metal ion binding
GO:0051262 IEA protein tetramerization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000073282 TP63 tumor protein p63 protein_coding Homo_sapiens
ENSMUSG00000022510 Trp63 transformation related protein 63 protein_coding Mus_musculus

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