C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: vav 2 guanine nucleotide exchange factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000044718 VAV2 7955 - 21:16534547-16597699 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000065717 VAV2-201 16536263-16581224 protein_coding
  ENSDART00000143987 VAV2-001 16534547-16597699 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverENSDART00000065717ENSDART00000143987
Transcript ID Brain Heart Kidney Liver
ENSDART00000065717 N/A 0.102±0.00 0.227±0.00 N/A
ENSDART00000143987 1.145±0.29 2.043±0.46 0.055±0.00 0.187±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000160293 VAV2 vav 2 guanine nucleotide exchange factor protein_coding Homo_sapiens
ENSMUSG00000009621 Vav2 vav 2 oncogene protein_coding Mus_musculus

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