C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: vav 2 oncogene
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000009621 Vav2 10090 - 2:27262104-27427033 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000056176 Vav2-001 27262104-27427033 protein_coding
  ENSMUST00000132642 Vav2-003 27302025-27344480 processed_transcript
  ENSMUST00000135584 Vav2-006 27269581-27271875 processed_transcript
  ENSMUST00000146843 Vav2-007 27269581-27271798 processed_transcript
  ENSMUST00000148067 Vav2-004 27268919-27278879 processed_transcript
  ENSMUST00000149758 Vav2-005 27268455-27277341 processed_transcript
  ENSMUST00000185188 Vav2-002 27262104-27426912 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000056176ENSMUST00000185188
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000056176 4.588±1.31 15.620±4.03 6.886±0.91 12.688±0.00 7.943±4.13 4.383±1.56 4.433±0.42 8.478±3.70 3.875±2.03 11.759±4.04 0.479±0.11 8.669±4.63 8.760±6.19 6.375±4.39
ENSMUST00000185188 N/A N/A N/A 6.811±1.24 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00014Y CIL_00014Y_0002 CGP 2:27188393-27427033
CIL_00014Z CIL_00014Z_0002 CGP 2:27262104-27507662

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0005085 IMP guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005154 IPI epidermal growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0007264 IMP small GTPase mediated signal transduction
GO:0010468 IEA regulation of gene expression
GO:0016477 IGI cell migration
GO:0030031 IGI cell projection assembly
GO:0030032 IGI lamellipodium assembly
GO:0030193 IEA regulation of blood coagulation
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0043547 IMP positive regulation of GTPase activity
GO:0043552 IGI positive regulation of phosphatidylinositol 3-kinase activity
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000044718 VAV2 vav 2 guanine nucleotide exchange factor protein_coding Danio_rerio
ENSG00000160293 VAV2 vav 2 guanine nucleotide exchange factor protein_coding Homo_sapiens

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