C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: vascular endothelial growth factor Aa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000045971 vegfaa 7955 + 16:4642220-4672554 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000128775 vegfaa-201 4642220-4672554 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000128775
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000128775 2.804±1.13 12.633±6.53 6.933±0.84 0.175±0.00 4.036±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0001568 IMP blood vessel development
GO:0001569 IMP patterning of blood vessels
GO:0001570 IMP vasculogenesis
GO:0001938 ISS positive regulation of endothelial cell proliferation
GO:0001944 IGI vasculature development
GO:0002040 IMP sprouting angiogenesis
GO:0002043 IDA blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO:0003262 IGI endocardial progenitor cell migration to the midline involved in heart field formation
GO:0005515 IPI protein binding
GO:0005576 IDA extracellular region
GO:0005622 IDA intracellular
GO:0007202 IDA activation of phospholipase C activity
GO:0007275 IEA multicellular organismal development
GO:0008016 IMP regulation of heart contraction
GO:0008045 IGI motor neuron axon guidance
GO:0008083 IEA growth factor activity
GO:0008201 IEA heparin binding
GO:0016020 IEA membrane
GO:0016310 IDA phosphorylation
GO:0030097 IDA hemopoiesis
GO:0030154 IEA cell differentiation
GO:0030878 IMP thyroid gland development
GO:0031334 ISS positive regulation of protein complex assembly
GO:0035477 IMP regulation of angioblast cell migration involved in selective angioblast sprouting
GO:0035479 IMP angioblast cell migration from lateral mesoderm to midline
GO:0043491 IDA protein kinase B signaling
GO:0048010 IGI vascular endothelial growth factor receptor signaling pathway
GO:0048793 IMP pronephros development
GO:0048844 IMP artery morphogenesis
GO:0050731 ISS positive regulation of peptidyl-tyrosine phosphorylation
GO:0051781 IEA positive regulation of cell division
GO:0051894 ISS positive regulation of focal adhesion assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000112715 VEGFA vascular endothelial growth factor A protein_coding Homo_sapiens
ENSMUSG00000023951 Vegfa vascular endothelial growth factor A protein_coding Mus_musculus

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