C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000052482 arhgef11 7955 - 7:6227373-6331608 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000017140 arhgef11-201 6227373-6314923 protein_coding
  ENSDART00000136594 arhgef11-001 6284139-6331608 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartMuscleENSDART00000017140ENSDART00000136594
Transcript ID Brain Heart Muscle
ENSDART00000017140 1.931±0.00 1.665±0.30 0.589±0.00
ENSDART00000136594 1.594±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001539 IMP ciliary or bacterial-type flagellar motility
GO:0001965 IPI G-protein alpha-subunit binding
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0007368 IMP determination of left/right symmetry
GO:0032956 IMP regulation of actin cytoskeleton organization
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043149 IDA stress fiber assembly
GO:0048840 IMP otolith development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000132694 ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 protein_coding Homo_sapiens
ENSMUSG00000041977 Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 protein_coding Mus_musculus

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