C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041977 Arhgef11 10090 + 3:87617559-87738034 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000039476 Arhgef11-001 87617575-87738033 protein_coding
  ENSMUST00000129113 Arhgef11-002 87617585-87735909 protein_coding
  ENSMUST00000136072 Arhgef11-004 87617559-87699145 retained_intron
  ENSMUST00000142799 Arhgef11-005 87617592-87717435 retained_intron
  ENSMUST00000152006 Arhgef11-003 87618101-87738034 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000039476ENSMUST00000129113ENSMUST00000152006
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000039476 7.957±0.42 8.322±1.23 4.313±0.00 2.858±0.45 N/A 6.907±0.00 3.394±0.29 5.493±1.05 1.235±0.27 10.631±0.17 1.984±0.66 7.739±3.32 3.292±1.15 5.037±0.00
ENSMUST00000129113 12.326±0.69 10.468±1.09 4.428±1.10 7.749±0.00 12.995±3.25 10.088±0.86 3.729±0.09 8.862±1.73 3.376±1.39 15.773±3.18 2.022±0.63 16.683±2.97 9.993±3.98 1.435±0.00
ENSMUST00000152006 N/A N/A N/A N/A 3.354±0.00 N/A N/A 4.417±0.00 N/A N/A 1.234±0.00 6.206±0.48 6.829±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001664 IEA G-protein coupled receptor binding
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0007266 IEA Rho protein signal transduction
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0045893 IEA positive regulation of transcription, DNA-templated

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052482 arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 protein_coding Danio_rerio
ENSG00000132694 ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 protein_coding Homo_sapiens

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