C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000054199 mthfd2l 7955 + 8:33237880-33251868 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000076350 mthfd2l-001 33237880-33251868 protein_coding
  ENSDART00000146901 mthfd2l-002 33237881-33247954 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyMuscleENSDART00000076350ENSDART00000146901
Transcript ID Brain Heart Kidney Muscle
ENSDART00000076350 0.451±0.00 0.161±0.16 0.572±0.00 N/A
ENSDART00000146901 N/A N/A N/A 0.076±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004477 IBA methenyltetrahydrofolate cyclohydrolase activity
GO:0004487 IBA methylenetetrahydrofolate dehydrogenase (NAD+) activity
GO:0004488 IEA methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0005739 IBA mitochondrion
GO:0006730 IBA one-carbon metabolic process
GO:0009396 IEA folic acid-containing compound biosynthetic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000163738 MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like protein_coding Homo_sapiens
ENSMUSG00000029376 Mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like protein_coding Mus_musculus

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