C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029376 Mthfd2l 10090 + 5:90931196-91021360 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000071652 Mthfd2l-201 90931196-91021360 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000071652
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000071652 1.849±0.81 4.231±0.83 2.903±0.13 9.388±6.19 2.358±0.89 2.207±0.64 1.308±0.26 1.135±0.28 0.864±0.56 2.396±0.29 0.947±0.25 3.620±1.70 0.543±0.28 0.701±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00035M CIL_00035M_0002 CGP 5:90903899-91021360
CIL_0006SN CIL_0006SN_0002 CGP 5:90931196-91035215

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000105 IEA histidine biosynthetic process
GO:0004477 IBA methenyltetrahydrofolate cyclohydrolase activity
GO:0004487 IBA methylenetetrahydrofolate dehydrogenase (NAD+) activity
GO:0004488 IBA methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0005739 IBA mitochondrion
GO:0005743 IEA mitochondrial inner membrane
GO:0006164 IEA purine nucleotide biosynthetic process
GO:0006730 IBA one-carbon metabolic process
GO:0009086 IEA methionine biosynthetic process
GO:0009396 IEA folic acid-containing compound biosynthetic process
GO:0035999 IEA tetrahydrofolate interconversion
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000054199 mthfd2l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like protein_coding Danio_rerio
ENSG00000163738 MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like protein_coding Homo_sapiens

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