Warning (512): _cake_core_ cache was unable to write 'cake_dev_eng' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'cake_dev_eng'
$value = array(
	'LC_MESSAGES' => array()
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
I18n::translate() - CORE/Cake/I18n/I18n.php, line 237
__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

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                ),
                E_USER_WARNING
            );
$key = 'default_citloci_list'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_citloci_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_citloci_list'
$value = array(
	(int) 0 => 'conserved_region_elements',
	(int) 1 => 'conserved_regions',
	(int) 2 => 'diffexp',
	(int) 3 => 'experiment',
	(int) 4 => 'expressed_transcripts',
	(int) 5 => 'external_accessions',
	(int) 6 => 'genes',
	(int) 7 => 'go_annotations',
	(int) 8 => 'homologues',
	(int) 9 => 'maptranscripttoregion',
	(int) 10 => 'organism',
	(int) 11 => 'sample',
	(int) 12 => 'study',
	(int) 13 => 'synonyms',
	(int) 14 => 'transcripts'
)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_citloci_genes' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_citloci_genes'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
DataSource::describe() - CORE/Cake/Model/Datasource/DataSource.php, line 135
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 332
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165

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                ),
                E_USER_WARNING
            );
$key = 'default_citloci_genes'
$value = array(
	'id' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 32,
		'key' => 'primary',
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'gene_version' => array(
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		'null' => true,
		'default' => null,
		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
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		'null' => false,
		'default' => null,
		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'assembly' => array(
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		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'chromosome' => array(
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		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
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	'strand' => array(
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		'collate' => 'latin1_swedish_ci',
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	'start' => array(
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	'gene_name' => array(
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		'null' => true,
		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'gene_source' => array(
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		'null' => true,
		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'gene_biotype' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 128,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'annotation_version' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'gene_description' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 128,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	)
)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/c-it-loci/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 372
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Gene::findByid() - APP/Controller/GeneController.php, line 302
GeneController::show() - APP/Controller/GeneController.php, line 302
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

• HOME
• REGIONS
• GENES
• TRANSCRIPTS
• HELP
• CONTACT

Gene Info
Description:	cereblon
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSDARG00000054250	crbn	7955	-	6:40387662-40397725	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSDART00000062724		crbn-001	40387662-40397725	protein_coding

Expression Patterns Heat Map Numeric Values Transcript ID Brain Heart Kidney Liver Muscle ENSDART00000062724 10.261±3.70 10.703±3.56 8.046±3.07 0.188±0.00 3.477±0.00

Conserved Regions
Gene is not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0004176	IEA	ATP-dependent peptidase activity
GO:0006508	IEA	proteolysis

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSG00000113851	CRBN	cereblon	protein_coding	Homo_sapiens
ENSMUSG00000005362	Crbn	cereblon	protein_coding	Mus_musculus

Loading

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                ),
                E_USER_WARNING
            );
$key = 'file_map'
$value = array(
	'Configure' => '/var/www/c-it-loci/lib/Cake/Core/Configure.php',
	'Hash' => '/var/www/c-it-loci/lib/Cake/Utility/Hash.php',
	'Cache' => '/var/www/c-it-loci/lib/Cake/Cache/Cache.php',
	'FileEngine' => '/var/www/c-it-loci/lib/Cake/Cache/Engine/FileEngine.php',
	'CacheEngine' => '/var/www/c-it-loci/lib/Cake/Cache/CacheEngine.php',
	'Inflector' => '/var/www/c-it-loci/lib/Cake/Utility/Inflector.php',
	'ErrorHandler' => '/var/www/c-it-loci/lib/Cake/Error/ErrorHandler.php',
	'CakePlugin' => '/var/www/c-it-loci/lib/Cake/Core/CakePlugin.php',
	'CakeLog' => '/var/www/c-it-loci/lib/Cake/Log/CakeLog.php',
	'LogEngineCollection' => '/var/www/c-it-loci/lib/Cake/Log/LogEngineCollection.php',
	'ObjectCollection' => '/var/www/c-it-loci/lib/Cake/Utility/ObjectCollection.php',
	'FileLog' => '/var/www/c-it-loci/lib/Cake/Log/Engine/FileLog.php',
	'BaseLog' => '/var/www/c-it-loci/lib/Cake/Log/Engine/BaseLog.php',
	'CakeLogInterface' => '/var/www/c-it-loci/lib/Cake/Log/CakeLogInterface.php',
	'Debugger' => '/var/www/c-it-loci/lib/Cake/Utility/Debugger.php',
	'String' => '/var/www/c-it-loci/lib/Cake/Utility/String.php',
	'Dispatcher' => '/var/www/c-it-loci/lib/Cake/Routing/Dispatcher.php',
	'CakeEventListener' => '/var/www/c-it-loci/lib/Cake/Event/CakeEventListener.php',
	'CakeRequest' => '/var/www/c-it-loci/lib/Cake/Network/CakeRequest.php',
	'CakeResponse' => '/var/www/c-it-loci/lib/Cake/Network/CakeResponse.php',
	'CakeEvent' => '/var/www/c-it-loci/lib/Cake/Event/CakeEvent.php',
	'CakeEventManager' => '/var/www/c-it-loci/lib/Cake/Event/CakeEventManager.php',
	'AssetDispatcher' => '/var/www/c-it-loci/lib/Cake/Routing/Filter/AssetDispatcher.php',
	'DispatcherFilter' => '/var/www/c-it-loci/lib/Cake/Routing/DispatcherFilter.php',
	'CacheDispatcher' => '/var/www/c-it-loci/lib/Cake/Routing/Filter/CacheDispatcher.php',
	'Router' => '/var/www/c-it-loci/lib/Cake/Routing/Router.php',
	'CakeRoute' => '/var/www/c-it-loci/lib/Cake/Routing/Route/CakeRoute.php',
	'PluginShortRoute' => '/var/www/c-it-loci/lib/Cake/Routing/Route/PluginShortRoute.php',
	'GeneController' => '/var/www/c-it-loci/app/Controller/GeneController.php',
	'AppController' => '/var/www/c-it-loci/app/Controller/AppController.php',
	'Controller' => '/var/www/c-it-loci/lib/Cake/Controller/Controller.php',
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	'Gene' => '/var/www/c-it-loci/app/Model/Gene.php',
	'AppModel' => '/var/www/c-it-loci/app/Model/AppModel.php',
	'Model' => '/var/www/c-it-loci/lib/Cake/Model/Model.php',
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	'DboSource' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/DboSource.php',
	'DataSource' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/DataSource.php',
	'I18n' => '/var/www/c-it-loci/lib/Cake/I18n/I18n.php',
	'L10n' => '/var/www/c-it-loci/lib/Cake/I18n/L10n.php',
	'CakeSession' => '/var/www/c-it-loci/lib/Cake/Model/Datasource/CakeSession.php',
	'View' => '/var/www/c-it-loci/lib/Cake/View/View.php',
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	'HtmlHelper' => '/var/www/c-it-loci/lib/Cake/View/Helper/HtmlHelper.php',
	'AppHelper' => '/var/www/c-it-loci/app/View/Helper/AppHelper.php',
	'Helper' => '/var/www/c-it-loci/lib/Cake/View/Helper.php',
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$config = '_cake_core_'
$settings = array(
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)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ??

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                ),
                E_USER_WARNING
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			(int) 6 => '`Gene`.`start`',
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			(int) 8 => '`Gene`.`gene_name`',
			(int) 9 => '`Gene`.`gene_source`',
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$config = '_cake_core_'
$settings = array(
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	'probability' => (int) 100,
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)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
[main] - [internal], line ??