C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: platelet-derived growth factor alpha a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000055505 pdgfaa 7955 - 22:26672330-26687102 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000105088 pdgfaa-201 26672330-26687102 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000105088
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000105088 2.469±1.12 1.066±0.18 10.025±5.97 0.194±0.00 1.984±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005161 IBA platelet-derived growth factor receptor binding
GO:0005615 IBA extracellular space
GO:0007275 IEP multicellular organismal development
GO:0007596 IBA blood coagulation
GO:0008083 IEA growth factor activity
GO:0008284 IBA positive regulation of cell proliferation
GO:0014068 IBA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IEA membrane
GO:0030335 IBA positive regulation of cell migration
GO:0031954 IBA positive regulation of protein autophosphorylation
GO:0043406 IBA positive regulation of MAP kinase activity
GO:0048008 IBA platelet-derived growth factor receptor signaling pathway
GO:0051781 IEA positive regulation of cell division
GO:0070374 IBA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000197461 PDGFA platelet-derived growth factor alpha polypeptide protein_coding Homo_sapiens
ENSMUSG00000025856 Pdgfa platelet derived growth factor, alpha protein_coding Mus_musculus

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