C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatase and tensin homolog B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000056623 ptenb 7955 - 12:18467401-18491723 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000079138 ptenb-002 18468915-18491723 protein_coding
  ENSDART00000079144 ptenb-001 18467401-18491711 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LiverMuscleENSDART00000079144
Transcript ID Liver Muscle
ENSDART00000079144 0.867±0.00 1.755±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0001568 IMP blood vessel development
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005515 IEA protein binding
GO:0006470 IEA protein dephosphorylation
GO:0008138 IEA protein tyrosine/serine/threonine phosphatase activity
GO:0008285 IEA negative regulation of cell proliferation
GO:0016311 IEA dephosphorylation
GO:0016314 IEA phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity
GO:0016791 IEA phosphatase activity
GO:0030097 IMP hemopoiesis
GO:0030165 IEA PDZ domain binding
GO:0030336 IEA negative regulation of cell migration
GO:0031174 IMP lifelong otolith mineralization
GO:0031647 IEA regulation of protein stability
GO:0042577 IMP lipid phosphatase activity
GO:0046855 IEA inositol phosphate dephosphorylation
GO:0046856 IEA phosphatidylinositol dephosphorylation
GO:0051800 IEA phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity
GO:0051895 IEA negative regulation of focal adhesion assembly
GO:0051896 IMP regulation of protein kinase B signaling
GO:0051898 IEA negative regulation of protein kinase B signaling
GO:0060027 IMP convergent extension involved in gastrulation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000171862 PTEN phosphatase and tensin homolog protein_coding Homo_sapiens
ENSMUSG00000013663 Pten phosphatase and tensin homolog protein_coding Mus_musculus

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