C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tryptophan hydroxylase 2 (tryptophan 5-monooxygenase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000057239 tph2 7955 - 18:16648932-16660224 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000079832 tph2-002 16648932-16660010 protein_coding
  ENSDART00000112627 tph2-001 16648932-16660224 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000079832ENSDART00000112627
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000079832 2.715±0.70 2.400±2.32 1.872±0.14 0.103±0.00 N/A
ENSDART00000112627 1.592±0.38 0.495±0.10 0.223±0.00 N/A 0.270±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003CY CIL_0003CY_0001 CGP 18:16648932-16679401

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004497 IEA monooxygenase activity
GO:0004510 IEA tryptophan 5-monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005575 ND cellular_component
GO:0008152 IEA metabolic process
GO:0009072 IEA aromatic amino acid family metabolic process
GO:0016597 IEA amino acid binding
GO:0016714 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
GO:0042427 IEA serotonin biosynthetic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000139287 TPH2 tryptophan hydroxylase 2 protein_coding Homo_sapiens
ENSMUSG00000006764 Tph2 tryptophan hydroxylase 2 protein_coding Mus_musculus

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