C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tryptophan hydroxylase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000139287 TPH2 9606 + 12:71938846-72186618 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000333850 TPH2-001 71938846-72032441 protein_coding
  ENST00000546576 TPH2-003 71938977-71965490 processed_transcript
  ENST00000547278 TPH2-004 72031314-72163152 processed_transcript
  ENST00000547348 TPH2-006 72031292-72186618 processed_transcript
  ENST00000550403 TPH2-007 72031272-72140442 processed_transcript
  ENST00000551074 TPH2-005 72031299-72147834 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalHeartMuscleOvaryPlacentaTestisENST00000546576ENST00000547348
Transcript ID Adrenal Heart Muscle Ovary Placenta Testis
ENST00000546576 0.302±0.00 0.141±0.00 0.075±0.00 0.047±0.00 N/A N/A
ENST00000547348 N/A N/A N/A 0.565±0.00 0.371±0.15 2.954±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004510 IEA tryptophan 5-monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005829 TAS cytosol
GO:0007623 IEA circadian rhythm
GO:0008152 IEA metabolic process
GO:0009072 IEA aromatic amino acid family metabolic process
GO:0014823 IEA response to activity
GO:0016597 IEA amino acid binding
GO:0016714 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen
GO:0031667 IEA response to nutrient levels
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042427 IEA serotonin biosynthetic process
GO:0043005 IEA neuron projection
GO:0043627 IEA response to estrogen
GO:0044281 TAS small molecule metabolic process
GO:0046219 TAS indolalkylamine biosynthetic process
GO:0051384 IEA response to glucocorticoid
GO:0051592 IEA response to calcium ion
GO:0055114 IEA oxidation-reduction process
GO:0071285 IEA cellular response to lithium ion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057239 tph2 tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) protein_coding Danio_rerio
ENSMUSG00000006764 Tph2 tryptophan hydroxylase 2 protein_coding Mus_musculus

Loading