C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tryptophan hydroxylase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000006764 Tph2 10090 - 10:115078641-115185022 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006949 Tph2-001 115078641-115185022 protein_coding
  ENSMUST00000155794 Tph2-002 115174080-115175558 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastLiverLungMuscleOvaryPlacentaTestisENSMUST00000006949ENSMUST00000155794
Transcript ID Adipose Bladder Brain Breast Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006949 0.036±0.02 0.003±0.00 0.663±0.32 0.071±0.00 0.002±0.00 0.018±0.00 0.023±0.01 0.081±0.04 0.010±0.00 0.356±0.15
ENSMUST00000155794 N/A N/A N/A N/A N/A N/A N/A 0.342±0.07 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003CY CIL_0003CY_0002 CGP 10:115078641-115251493

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004510 IDA tryptophan 5-monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0006587 IC serotonin biosynthetic process from tryptophan
GO:0007623 IEA circadian rhythm
GO:0014823 IEA response to activity
GO:0016597 IEA amino acid binding
GO:0031667 IEA response to nutrient levels
GO:0043005 IDA neuron projection
GO:0043627 IEA response to estrogen
GO:0051384 IEA response to glucocorticoid
GO:0051592 IEA response to calcium ion
GO:0055114 IEA oxidation-reduction process
GO:0071285 IEA cellular response to lithium ion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057239 tph2 tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) protein_coding Danio_rerio
ENSG00000139287 TPH2 tryptophan hydroxylase 2 protein_coding Homo_sapiens

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