C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X-C motif) receptor 4a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000057633 cxcr4a 7955 + 6:12833922-12835647 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000080350 cxcr4a-001 12833922-12835647 protein_coding
  ENSDART00000149018 cxcr4a-002 12834038-12835264 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000080350ENSDART00000149018
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000080350 0.851±0.66 1.118±0.75 8.809±5.37 N/A N/A
ENSDART00000149018 0.926±0.00 1.147±0.00 N/A 0.074±0.00 2.341±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000902 IMP cell morphogenesis
GO:0001570 IMP vasculogenesis
GO:0002040 IMP sprouting angiogenesis
GO:0002042 IGI cell migration involved in sprouting angiogenesis
GO:0004871 IEA signal transducer activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0004950 IEA chemokine receptor activity
GO:0006935 IEA chemotaxis
GO:0007165 IEA signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0016494 IEA C-X-C chemokine receptor activity
GO:0030239 IMP myofibril assembly
GO:0042074 IMP cell migration involved in gastrulation
GO:0042119 IEA neutrophil activation
GO:0055002 IMP striated muscle cell development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000121966 CXCR4 chemokine (C-X-C motif) receptor 4 protein_coding Homo_sapiens
ENSMUSG00000045382 Cxcr4 chemokine (C-X-C motif) receptor 4 protein_coding Mus_musculus

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