C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: platelet derived growth factor alpha b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000058424 pdgfab 7955 + 3:12296686-12342171 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000055993 pdgfab-001 12296686-12342171 protein_coding
  ENSDART00000147888 pdgfab-002 12334207-12341496 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverENSDART00000055993
Transcript ID Brain Heart Kidney Liver
ENSDART00000055993 0.758±0.42 0.611±0.40 0.927±0.34 0.077±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005161 IBA platelet-derived growth factor receptor binding
GO:0005615 IBA extracellular space
GO:0007596 IBA blood coagulation
GO:0008083 IEA growth factor activity
GO:0008284 IBA positive regulation of cell proliferation
GO:0014068 IBA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IEA membrane
GO:0030335 IBA positive regulation of cell migration
GO:0031954 IBA positive regulation of protein autophosphorylation
GO:0043406 IBA positive regulation of MAP kinase activity
GO:0048008 IBA platelet-derived growth factor receptor signaling pathway
GO:0051781 IEA positive regulation of cell division
GO:0070374 IBA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000197461 PDGFA platelet-derived growth factor alpha polypeptide protein_coding Homo_sapiens
ENSMUSG00000025856 Pdgfa platelet derived growth factor, alpha protein_coding Mus_musculus

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