C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lymphocyte-specific protein tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000059282 lck 7955 - 17:25134652-25224210 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000082356 lck-201 25134680-25168218 protein_coding
  ENSDART00000105478 lck-202 25134657-25224210 protein_coding
  ENSDART00000126663 lck-002 25134652-25172294 protein_coding
  ENSDART00000148860 lck-001 25134654-25172285 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyMuscleENSDART00000082356ENSDART00000105478ENSDART00000148860
Transcript ID Brain Heart Kidney Muscle
ENSDART00000082356 0.185±0.08 3.110±0.17 3.570±2.58 0.069±0.00
ENSDART00000105478 0.164±0.06 0.410±0.00 0.876±0.00 N/A
ENSDART00000148860 N/A 0.737±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000182866 LCK LCK proto-oncogene, Src family tyrosine kinase protein_coding Homo_sapiens
ENSMUSG00000000409 Lck lymphocyte protein tyrosine kinase protein_coding Mus_musculus

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