C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: delta-like 4 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000070425 dll4 7955 + 20:28274771-28283631 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000103320 dll4-001 28274771-28283631 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000103320
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000103320 2.727±0.52 10.648±2.25 2.217±0.52 0.582±0.00 3.550±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005IN CIL_0005IN_0001 CGP 20:28274771-28299069

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0001569 IGI patterning of blood vessels
GO:0001946 IMP lymphangiogenesis
GO:0002040 IGI sprouting angiogenesis
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0007154 IEA cell communication
GO:0007219 IEA Notch signaling pathway
GO:0007275 IEA multicellular organismal development
GO:0016020 IEA membrane
GO:0016021 IEA integral to membrane
GO:0030947 IMP regulation of vascular endothelial growth factor receptor signaling pathway
GO:0043534 IMP blood vessel endothelial cell migration
GO:0043537 IMP negative regulation of blood vessel endothelial cell migration
GO:0045765 IGI regulation of angiogenesis
GO:0060840 IMP artery development
GO:0060841 IMP venous blood vessel development
GO:0060854 IMP patterning of lymph vessels
GO:0060855 IMP venous endothelial cell migration involved in lymph vessel development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000128917 DLL4 delta-like 4 (Drosophila) protein_coding Homo_sapiens
ENSMUSG00000027314 Dll4 delta-like 4 (Drosophila) protein_coding Mus_musculus

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