C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled receptor kinase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000070448 grk4 7955 + 1:11316763-11387524 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000066638 grk4-201 11316763-11387524 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000066638
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000066638 0.117±0.05 0.344±0.36 0.197±0.15 0.035±0.00 0.132±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004703 IEA G-protein coupled receptor kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005575 ND cellular_component
GO:0006468 IEA protein phosphorylation
GO:0007165 IEA signal transduction
GO:0016301 IEA kinase activity
GO:0016310 IEA phosphorylation
GO:0016740 IEA transferase activity
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0085033 IMP positive regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000125388 GRK4 G protein-coupled receptor kinase 4 protein_coding Homo_sapiens
ENSMUSG00000052783 Grk4 G protein-coupled receptor kinase 4 protein_coding Mus_musculus

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