C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled receptor kinase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000052783 Grk4 10090 + 5:34660379-34755305 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001112 Grk4-001 34660379-34755303 protein_coding
  ENSMUST00000074651 Grk4-002 34660379-34701083 protein_coding
  ENSMUST00000134217 Grk4-003 34744443-34755305 processed_transcript
  ENSMUST00000148588 Grk4-005 34660975-34674715 protein_coding
  ENSMUST00000153323 Grk4-004 34710133-34745337 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001112ENSMUST00000074651ENSMUST00000134217ENSMUST00000153323
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001112 0.360±0.06 1.023±0.32 1.307±0.30 0.375±0.00 0.543±0.24 0.730±0.48 0.117±0.04 0.192±0.03 0.196±0.15 0.495±0.17 0.245±0.09 0.849±0.32 0.158±0.09 20.064±6.20
ENSMUST00000074651 0.325±0.09 0.765±0.55 0.282±0.00 0.879±0.41 0.670±0.54 0.546±0.12 0.304±0.02 0.315±0.15 0.152±0.07 0.484±0.22 0.142±0.03 0.665±0.11 0.229±0.07 N/A
ENSMUST00000134217 N/A N/A N/A N/A 0.624±0.00 N/A 0.197±0.00 N/A N/A N/A 0.318±0.04 N/A N/A N/A
ENSMUST00000153323 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 62.964±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00056M CIL_00056M_0002 CGP 5:34638532-34755305
CIL_000748 CIL_000748_0002 CGP 5:34660379-34912534

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002029 IEA desensitization of G-protein coupled receptor protein signaling pathway
GO:0002031 IEA G-protein coupled receptor internalization
GO:0004703 IEA G-protein coupled receptor kinase activity
GO:0005524 IEA ATP binding
GO:0005829 IEA cytosol
GO:0007165 IEA signal transduction
GO:0030425 IEA dendrite
GO:0031623 IEA receptor internalization
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043025 IEA neuronal cell body
GO:0050254 IEA rhodopsin kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070448 grk4 G protein-coupled receptor kinase 4 protein_coding Danio_rerio
ENSDARG00000070460 grk4 G protein-coupled receptor kinase 4 protein_coding Danio_rerio
ENSG00000125388 GRK4 G protein-coupled receptor kinase 4 protein_coding Homo_sapiens

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