C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000071692 PREX2 7955 + 24:19498092-19756483 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000106186 PREX2-001 19498092-19756483 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000106186
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000106186 3.805±2.55 4.756±1.61 0.723±0.00 0.137±0.00 3.276±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005BU CIL_0005BU_0001 CGP 24:19433056-19756483
CIL_0001SD CIL_0001SD_0001 CGP 24:19498092-19938011

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000046889 PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 protein_coding Homo_sapiens
ENSMUSG00000048960 Prex2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 protein_coding Mus_musculus

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