C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 7b
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000073848 arhgef7b 7955 + 1:46429125-46517387 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000042086 arhgef7b-201 46464645-46517372 protein_coding
  ENSDART00000108528 arhgef7b-202 46429125-46517387 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000042086ENSDART00000108528
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000042086 2.866±0.00 2.448±0.00 6.772±3.46 0.165±0.00 0.915±0.00
ENSDART00000108528 5.478±2.62 5.521±1.94 1.513±0.00 0.404±0.00 0.918±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0001568 IMP blood vessel development
GO:0001935 IMP endothelial cell proliferation
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035556 IEA intracellular signal transduction
GO:0055113 IMP epiboly involved in gastrulation with mouth forming second
GO:0071896 IMP protein localization to adherens junction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000102606 ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 protein_coding Homo_sapiens
ENSMUSG00000031511 Arhgef7 Rho guanine nucleotide exchange factor (GEF7) protein_coding Mus_musculus

Loading