Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSDARG00000074457	PFKFB1 (2 of 2)	7955	-	23:12794758-12900222	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSDART00000012724		PFKFB1 (2 of 2)-201	12898878-12900103	protein_coding
	ENSDART00000103231		PFKFB1 (2 of 2)-202	12794758-12819344	protein_coding
	ENSDART00000135103		PFKFB1 (2 of 2)-002	12853565-12899379	retained_intron
	ENSDART00000139166		PFKFB1 (2 of 2)-001	12794764-12847424	protein_coding
	ENSDART00000146640		PFKFB1 (2 of 2)-003	12853853-12900222	protein_coding

Expression Patterns

Transcript ID	Brain	Heart	Kidney	Liver	Muscle
ENSDART00000012724	N/A	N/A	N/A	0.757±0.00	N/A
ENSDART00000103231	0.109±0.02	0.269±0.00	N/A	N/A	N/A
ENSDART00000135103	0.233±0.00	1.818±0.79	N/A	0.275±0.00	N/A
ENSDART00000139166	N/A	N/A	1.328±0.77	0.763±0.00	N/A
ENSDART00000146640	N/A	0.093±0.00	N/A	0.280±0.00	0.092±0.00

Conserved Regions
Gene is not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0003676	IEA	nucleic acid binding
GO:0003824	IEA	catalytic activity
GO:0003873	IEA	6-phosphofructo-2-kinase activity
GO:0004331	IEA	fructose-2,6-bisphosphate 2-phosphatase activity
GO:0005524	IEA	ATP binding
GO:0006000	IEA	fructose metabolic process
GO:0006003	IEA	fructose 2,6-bisphosphate metabolic process
GO:0008152	IEA	metabolic process
GO:0046983	IEA	protein dimerization activity

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSG00000158571	PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	protein_coding	Homo_sapiens
ENSMUSG00000025271	Pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	protein_coding	Mus_musculus

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