C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025271 Pfkfb1 10090 + X:150588229-150643878 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000080884 Pfkfb1-001 150589921-150643878 protein_coding
  ENSMUST00000112713 Pfkfb1-002 150594478-150643878 protein_coding
  ENSMUST00000124381 Pfkfb1-005 150588256-150612932 processed_transcript
  ENSMUST00000142848 Pfkfb1-006 150613934-150624706 processed_transcript
  ENSMUST00000150783 Pfkfb1-003 150594610-150643857 retained_intron
  ENSMUST00000153221 Pfkfb1-004 150588229-150625183 protein_coding
  ENSMUST00000154528 Pfkfb1-007 150625341-150641977 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartLiverMuscleOvaryPlacentaTestisENSMUST00000080884ENSMUST00000112713
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Liver Muscle Ovary Placenta Testis
ENSMUST00000080884 26.742±13.14 7.181±4.73 1.800±0.73 22.905±7.13 1.634±0.54 N/A N/A 16.971±1.65 5.302±1.04 13.649±1.58 2.801±0.06
ENSMUST00000112713 3.867±0.00 3.481±0.00 N/A 8.695±1.98 N/A 7.710±0.29 34.203±35.77 8.038±2.42 3.778±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YC CIL_0000YC_0002 CGP X:150519519-150589868

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003873 IEA 6-phosphofructo-2-kinase activity
GO:0004331 ISS fructose-2,6-bisphosphate 2-phosphatase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0006000 IEA fructose metabolic process
GO:0006003 ISS fructose 2,6-bisphosphate metabolic process
GO:0016311 IEA dephosphorylation
GO:0019900 IEA kinase binding
GO:0031100 IEA organ regeneration
GO:0032868 IEA response to insulin
GO:0033133 IEA positive regulation of glucokinase activity
GO:0033762 IEA response to glucagon
GO:0042594 IEA response to starvation
GO:0042802 IEA identical protein binding
GO:0043540 IEA 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex
GO:0046835 IEA carbohydrate phosphorylation
GO:0051384 IEA response to glucocorticoid
GO:0051591 IEA response to cAMP
GO:0070095 IEA fructose-6-phosphate binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037140 pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 protein_coding Danio_rerio
ENSDARG00000074457 PFKFB1 (2 of 2) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 protein_coding Danio_rerio
ENSG00000158571 PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 protein_coding Homo_sapiens

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