C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000075347 chfr 7955 + 5:19558987-19591811 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000110783 chfr-001 19558987-19591811 protein_coding
  ENSDART00000115227 chfr-201 19559035-19591810 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000110783ENSDART00000115227
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000110783 1.948±0.81 3.419±1.82 7.775±2.58 1.119±0.00 1.140±0.00
ENSDART00000115227 2.753±0.00 1.549±0.73 9.794±0.00 0.507±0.00 0.981±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 ISS nucleotide binding
GO:0000209 ISS protein polyubiquitination
GO:0004842 ISS ubiquitin-protein ligase activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0007049 IEA cell cycle
GO:0007067 IEA mitosis
GO:0007093 ISS mitotic cell cycle checkpoint
GO:0008270 IEA zinc ion binding
GO:0016605 ISS PML body
GO:0016874 IEA ligase activity
GO:0019941 ISS modification-dependent protein catabolic process
GO:0046872 IEA metal ion binding
GO:0051301 IEA cell division

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000072609 CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase protein_coding Homo_sapiens
ENSMUSG00000014668 Chfr checkpoint with forkhead and ring finger domains protein_coding Mus_musculus

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