C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: checkpoint with forkhead and ring finger domains
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000014668 Chfr 10090 + 5:110135840-110171972 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000014812 Chfr-201 110135840-110171972 protein_coding
  ENSMUST00000112519 Chfr-202 110135840-110171972 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000014812ENSMUST00000112519
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000014812 2.856±1.49 3.300±0.95 2.260±0.20 7.263±0.00 2.535±0.00 5.103±1.26 1.048±0.00 1.735±0.52 2.299±0.82 3.011±0.53 2.108±0.75 2.931±0.66 3.495±0.25 3.952±0.64
ENSMUST00000112519 3.886±1.25 7.573±2.77 6.618±0.96 18.694±1.39 7.316±1.59 10.256±1.26 2.102±0.72 3.607±0.96 5.049±1.94 4.185±1.97 2.894±1.08 5.822±1.35 9.707±4.08 10.393±5.82

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 ISS nucleotide binding
GO:0000209 IDA protein polyubiquitination
GO:0000278 IMP mitotic cell cycle
GO:0004842 IMP ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0006511 IDA ubiquitin-dependent protein catabolic process
GO:0007067 IEA mitotic nuclear division
GO:0007093 ISS mitotic cell cycle checkpoint
GO:0008270 IEA zinc ion binding
GO:0016605 ISS PML body
GO:0016874 IEA ligase activity
GO:0019941 IEA modification-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075347 chfr checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase protein_coding Danio_rerio
ENSG00000072609 CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase protein_coding Homo_sapiens

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