C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: platelet derived growth factor, B polypeptide
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000086778 pdgfb 7955 - 22:31884638-31907995 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000121599 pdgfb-201 31884638-31907610 protein_coding
  ENSDART00000132776 pdgfb-001 31887995-31907995 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartENSDART00000121599ENSDART00000132776
Transcript ID Brain Heart
ENSDART00000121599 0.091±0.00 0.231±0.12
ENSDART00000132776 0.125±0.00 0.166±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0005161 IBA platelet-derived growth factor receptor binding
GO:0005615 IBA extracellular space
GO:0006275 IDA regulation of DNA replication
GO:0007596 IBA blood coagulation
GO:0008083 IEA growth factor activity
GO:0008284 IBA positive regulation of cell proliferation
GO:0014068 IBA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IEA membrane
GO:0030335 IBA positive regulation of cell migration
GO:0031954 IBA positive regulation of protein autophosphorylation
GO:0042246 IEP tissue regeneration
GO:0043406 IBA positive regulation of MAP kinase activity
GO:0048008 IBA platelet-derived growth factor receptor signaling pathway
GO:0048514 IMP blood vessel morphogenesis
GO:0051781 IEA positive regulation of cell division
GO:0070374 IBA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000100311 PDGFB platelet-derived growth factor beta polypeptide protein_coding Homo_sapiens
ENSMUSG00000000489 Pdgfb platelet derived growth factor, B polypeptide protein_coding Mus_musculus

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