C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000088180 map3k1 7955 + 10:7894109-7992183 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000126052 map3k1-201 7894109-7992183 protein_coding
  ENSDART00000139062 map3k1-001 7940416-7990492 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000126052ENSDART00000139062
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000126052 1.318±0.29 1.789±0.68 4.561±1.59 0.360±0.00 1.485±0.00
ENSDART00000139062 N/A 0.438±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005488 IEA binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0006468 IEA protein phosphorylation
GO:0008270 IEA zinc ion binding
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000095015 MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase protein_coding Homo_sapiens
ENSMUSG00000021754 Map3k1 mitogen-activated protein kinase kinase kinase 1 protein_coding Mus_musculus

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