C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: deiodinase, iodothyronine, type II
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000094857 dio2 7955 + 17:16714656-16717991 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000146276 dio2-001 16714656-16717991 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000146276
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000146276 24.426±4.48 1.276±0.72 49.762±4.16 80.709±0.00 6.347±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004800 IEA thyroxine 5'-deiodinase activity
GO:0009725 IDA response to hormone
GO:0009790 IMP embryo development
GO:0016491 IEA oxidoreductase activity
GO:0042446 IEA hormone biosynthetic process
GO:0048066 IMP developmental pigmentation
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000211448 DIO2 deiodinase, iodothyronine, type II protein_coding Homo_sapiens
ENSMUSG00000007682 Dio2 deiodinase, iodothyronine, type II protein_coding Mus_musculus

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