C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: deiodinase, iodothyronine, type II
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000007682 Dio2 10090 - 12:90724554-90738438 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000082432 Dio2-201 90724554-90738438 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000082432
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000082432 28.283±27.63 0.904±0.27 0.550±0.17 1.467±1.97 0.483±0.13 0.044±0.03 0.450±0.04 0.334±0.08 0.051±0.01 0.482±0.34 0.151±0.04 3.267±1.35 0.095±0.11 0.952±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004U0 CIL_0004U0_0002 CGP 12:88722876-90738438
CIL_0004TZ CIL_0004TZ_0002 CGP 12:90724554-91384409

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004800 IMP thyroxine 5'-deiodinase activity
GO:0016021 IEA integral component of membrane
GO:0042404 IMP thyroid hormone catabolic process
GO:0042446 IEA hormone biosynthetic process
GO:0055114 IEA oxidation-reduction process
GO:0070460 TAS thyroid-stimulating hormone secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000094857 dio2 deiodinase, iodothyronine, type II protein_coding Danio_rerio
ENSG00000211448 DIO2 deiodinase, iodothyronine, type II protein_coding Homo_sapiens

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