C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: wingless-type MMTV integration site family, member 16
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000002745 WNT16 9606 + 7:121325367-121341104 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000222462 WNT16-001 121329003-121341104 protein_coding
  ENST00000361301 WNT16-002 121325367-121339458 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000222462ENST00000361301
Transcript ID Adrenal Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000222462 0.091±0.00 0.147±0.00 0.028±0.01 0.072±0.01 N/A 0.011±0.00 0.011±0.00 N/A 0.028±0.02 0.371±0.36 0.135±0.12
ENST00000361301 N/A N/A N/A 0.213±0.00 0.018±0.00 0.165±0.00 N/A 0.035±0.00 0.063±0.03 0.359±0.24 0.123±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004XW CIL_0004XW_0002 CGP 7:120988677-121341104
CIL_0003R0 CIL_0003R0_0001 CGP 7:121325367-121396364

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003408 ISS optic cup formation involved in camera-type eye development
GO:0005102 IEA receptor binding
GO:0005109 IBA frizzled binding
GO:0005576 TAS:IEA extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0007275 IEA multicellular organismal development
GO:0010628 IMP positive regulation of gene expression
GO:0014068 IMP positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016055 IBA:IEA Wnt signaling pathway
GO:0030182 IBA neuron differentiation
GO:0030216 IMP keratinocyte differentiation
GO:0043616 IMP keratinocyte proliferation
GO:0045165 IBA cell fate commitment
GO:0046330 IMP positive regulation of JNK cascade
GO:0046849 IEA bone remodeling
GO:0060317 IEA cardiac epithelial to mesenchymal transition
GO:0060548 IMP negative regulation of cell death
GO:0090399 IMP replicative senescence
GO:0090403 IMP oxidative stress-induced premature senescence

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000094973 wnt16 wingless-type MMTV integration site family, member 16 protein_coding Danio_rerio
ENSMUSG00000029671 Wnt16 wingless-type MMTV integration site family, member 16 protein_coding Mus_musculus

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